{"id":13160,"date":"2026-01-29T12:11:55","date_gmt":"2026-01-29T12:11:55","guid":{"rendered":"https:\/\/diyhaven858.wasmer.app\/index.php\/how-opvee-indiviors-powerful-overdose-antidote-went-bust\/"},"modified":"2026-01-29T12:11:55","modified_gmt":"2026-01-29T12:11:55","slug":"how-opvee-indiviors-powerful-overdose-antidote-went-bust","status":"publish","type":"post","link":"https:\/\/diyhaven858.wasmer.app\/index.php\/how-opvee-indiviors-powerful-overdose-antidote-went-bust\/","title":{"rendered":"How Opvee, Indivior\u2019s powerful overdose antidote, went bust"},"content":{"rendered":"<p> <br \/>\n<\/p>\n<div>\n<p>It was cast as a lifesaving medication, a \u201cbest-in-class\u201d overdose antidote built specifically for the fentanyl era. It was far more powerful than Narcan, the nasal spray it was designed to supplant. Data suggested that the newer spray, Opvee, would restore breathing faster, averting death and brain injury for thousands of Americans who experience an opioid overdose. As billions of opioid settlement dollars became available to public health programs, the medication\u2019s manufacturer projected annual profits as high as $250 million.<\/p>\n<p>There was just one problem: The people Opvee was designed to help didn\u2019t want it.\u00a0<\/p>\n<p>Barely two years since its launch, the medication\u2019s manufacturer, Indivior, has largely abandoned it. Opvee had become more trouble than it was worth: It was a lightning rod among harm reduction organizations, who saw the nasal spray as unnecessary and, because it could cause severe withdrawal, actively harmful to drug users\u2019 well-being. Demand was meager, even before New York\u2019s attorney general launched an investigation into Indivior\u2019s sales tactics. In September, the company stopped marketing the medication altogether.\u00a0<\/p>\n<div class=\"restricted-content-breaker article\" aria-labelledby=\"restricted-story-heading\" aria-describedby=\"restricted-story-description\" checked=\"false\">\n<div class=\"restricted-content-breaker-bar\">\n<p class=\"restricted-text\">STAT+ Exclusive Story<\/p>\n<p class=\"restricted-login\">Already have an account? 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Log in<\/p>\n<div class=\"restricted-content-breaker-cards\">\n<div class=\"slider-container\" aria-label=\"Subscription plan toggle\">\n\t\t\t\t\t\t<button type=\"button\" class=\"individual\" aria-pressed=\"false\">Individual plans<\/button><\/p>\n<p>\t\t\t\t\t\t<button type=\"button\" class=\"group\" aria-pressed=\"false\">Group plans<\/button>\n\t\t\t\t\t<\/div>\n<\/p><\/div>\n<p>\t\t\t\tView All Plans\n\t\t\t<\/p><\/div>\n<\/p><\/div>\n<div class=\"restricted-message-breaker\">\n<div class=\"restricted-content-wrapper\">\n<div class=\"restricted-content-message\">\n<p class=\"restricted-content-text\">\n\t\t\t\t\t\tTo read the rest of this story subscribe to STAT+.\t\t\t\t\t<\/p>\n<p>\t\t\t\t\tSubscribe\n\t\t\t\t\t\t\t\t\t<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<p><br \/>\n<br \/><<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>It was cast as a lifesaving medication, a \u201cbest-in-class\u201d overdose antidote built specifically for the fentanyl era. It was far more powerful than Narcan, the nasal spray it was designed to supplant. Data suggested that the newer spray, Opvee, would restore breathing faster, averting death and brain injury for thousands of Americans who experience an [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":13161,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_daextam_enable_autolinks":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[2],"tags":[],"class_list":["post-13160","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/diyhaven858.wasmer.app\/wp-content\/uploads\/2026\/01\/OpVee2-1-1024x576.jpg","jetpack_sharing_enabled":true,"jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/posts\/13160","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/comments?post=13160"}],"version-history":[{"count":0,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/posts\/13160\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/media\/13161"}],"wp:attachment":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/media?parent=13160"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/categories?post=13160"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/tags?post=13160"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}