{"id":14143,"date":"2026-01-30T13:19:15","date_gmt":"2026-01-30T13:19:15","guid":{"rendered":"https:\/\/diyhaven858.wasmer.app\/index.php\/psychiatric-disorders-may-double-the-risk-for-acs\/"},"modified":"2026-01-30T13:19:15","modified_gmt":"2026-01-30T13:19:15","slug":"psychiatric-disorders-may-double-the-risk-for-acs","status":"publish","type":"post","link":"https:\/\/diyhaven858.wasmer.app\/index.php\/psychiatric-disorders-may-double-the-risk-for-acs\/","title":{"rendered":"Psychiatric Disorders May Double the Risk for ACS"},"content":{"rendered":"


\n<\/p>\n

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TOPLINE:<\/h2>\n

Anxiety, depression, and sleep disorders were each associated with an increased risk for acute coronary syndrome (ACS), with posttraumatic stress disorder (PTSD) linked to a nearly threefold higher risk for ACS than in individuals without the disorder, a new meta-analysis with more than 22 million participants showed.<\/p>\n

METHODOLOGY:<\/h2>\n
    \n
  • A systematic review and meta-analysis from 2024 to 2025 included 25 studies, of which 18 were retrospective cohort studies, six were prospective cohort studies, and one was a case-control study.<\/li>\n
  • Data for more than 22 million participants (median age, 48 years; 59% male) were analyzed; 13% of participants were diagnosed with mental disorders at baseline, and 1% had experienced an ACS event.<\/li>\n
  • The disorders the investigators primarily focused on were anxiety, depression, and substance use disorders.<\/li>\n
  • The primary outcome was the association between mental disorders and risk for ACS, including acute myocardial infarction (MI).<\/li>\n<\/ul>\n

    TAKEAWAY:<\/h2>\n
      \n
    • PTSD was associated with the strongest risk for acute MI (hazard ratio [HR], 2.7; P<\/em> < .001), followed by anxiety (HR, 1.6; P<\/em> < .001). Participants with substance use disorders also had increased odds of having acute MI (odds ratio, 2.4; P\u00a0<\/em>= .01).<\/li>\n
    • Depressive disorders (HR, 1.4; P<\/em> = .01) and sleep disorders (HR, 1.6; P<\/em> < .001) were each linked to an increased risk for ACS events.<\/li>\n
    • Bipolar or psychotic disorders were not significantly associated with increased risk for acute MI.<\/li>\n<\/ul>\n

      IN PRACTICE:<\/h2>\n

      \u201cIntegrating mental health screening and management into cardiovascular care could significantly improve outcomes and reduce the burden of ACS among individuals with mental health disorders,\u201d the investigators of the study wrote.<\/p>\n

      SOURCE:<\/h2>\n

      The study was led by Arnav Gupta, MD, University of Calgary, Calgary, Alberta, Canada. It was published online on January 14 in JAMA Psychiatry<\/em>.<\/p>\n

      LIMITATIONS:<\/h2>\n

      The study was limited by heterogeneity from diverse samples, varied study designs, inconsistent covariate adjustments, and underreporting of baseline characteristics, including precise follow-up durations, acute MI types, and psychotropic medication details. Administrative claims data may have introduced a misclassification bias due to diagnostic criteria heterogeneity.<\/p>\n

      DISCLOSURES:<\/h2>\n

      No funding information was provided in the study. One investigator reported receiving honoraria or consultant fees from various pharmaceutical companies, which are fully listed in the original article. The other investigators reported having no relevant financial disclosures.<\/p>\n

      This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.<\/em><\/p>\n<\/div>\n<\/div>\n


      \n
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      TOPLINE: Anxiety, depression, and sleep disorders were each associated with an increased risk for acute coronary syndrome (ACS), with posttraumatic stress disorder (PTSD) linked to a nearly threefold higher risk for ACS than in individuals without the disorder, a new meta-analysis with more than 22 million participants showed. METHODOLOGY: A systematic review and meta-analysis from […]<\/p>\n","protected":false},"author":1,"featured_media":14144,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_daextam_enable_autolinks":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[2],"tags":[],"class_list":["post-14143","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/diyhaven858.wasmer.app\/wp-content\/uploads\/2026\/01\/dt-260130-young-woman-chect-pain-800x450.jpg","jetpack_sharing_enabled":true,"jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/posts\/14143","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/comments?post=14143"}],"version-history":[{"count":0,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/posts\/14143\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/media\/14144"}],"wp:attachment":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/media?parent=14143"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/categories?post=14143"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/tags?post=14143"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}