TOPLINE:<\/h2>\n
In a pooled analysis of 25 studies from 23 countries, a two-question screening tool demonstrated excellent diagnostic accuracy for identifying individuals with hidradenitis suppurativa (HS), with a pooled sensitivity of 0.88 and specificity of 0.86.<\/p>\n
METHODOLOGY:<\/h2>\n\n- Researchers evaluated the diagnostic accuracy of a screening questionnaire validated and used in the Global HS Atlas (GHiSA) Global Prevalence Studies to detect HS in healthy adults accompanying patients undergoing care at hospitals or clinics; the pooled analysis included data from 25 studies across 23 countries.<\/li>\n
- Participants completed a screening questionnaire with two questions: \u201cHave you had outbreaks of boils during the last 6 months?\u201d and \u201cHave you for the past 6 months had two or more boils\/abscesses in any of the below locations with five different location options [axilla, groin, genitals, under the breasts, and other locations, eg, perianal, neck, and abdomen]?\u201d A positive screen was yes to both questions.<\/li>\n
- All screen-positive and approximately 10% of screen-negative participants underwent clinical examination.<\/li>\n<\/ul>\n
TAKEAWAY:<\/h2>\n\n- Sensitivity (0.43-1.00) and specificity (0.15-1.00) values varied globally. The pooled sensitivity of the screening questionnaire was 0.88, indicating a high ability to detect HS. The pooled specificity was 0.86, showing good discrimination of individuals without HS.<\/li>\n
- The area under the summary receiver operating curve was 0.93, indicating excellent diagnostic accuracy.<\/li>\n
- The positive predictive value ranged from 0.05 to 1.00, and the negative predictive value ranged from 0.97 to 1.00, with 17 of 23 countries reporting a negative predictive value of 1.00.<\/li>\n
- The Quality Assessment of Diagnostic Accuracy Studies-2 tool assessment rated risk for bias as high for the \u201creference standard\u201d and for the \u201cpatient flow\u201d domain; there were applicability concerns for patient selection.<\/li>\n<\/ul>\n
IN PRACTICE:<\/h2>\n
\u201cThe results demonstrate a high diagnostic accuracy (pooled sensitivity, 0.88; and specificity, 0.86) of the screening questionnaire in detecting HS in healthy adults,\u201d the study authors wrote. This questionnaire, they concluded, \u201cmay prove useful in triaging, ensuring that only individuals fitting the criteria see specialized dermatological care.\u201d<\/p>\n
SOURCE:<\/h2>\n
The study was led by Dorra Bouazzi, Department of Dermatology, Zealand University Hospital, Roskilde, Denmark, and was published online on January 9 in the British Journal of Dermatology<\/em>.<\/p>\nLIMITATIONS:<\/h2>\n
The exclusive inclusion of GHiSA studies may have limited the generalizability of the findings. The study had a high risk for bias in reference standard and patient flow domains, which lowered the validity of the study. Additionally, the absence of likelihood ratios limited comprehensive assessment of the diagnostic test.<\/p>\n
DISCLOSURES:<\/h2>\n
Bouazzi reported receiving research grant support from Region Sjaelland \u2013 Medicinsporet. The Section for Biostatistics and Evidence-Based Research at the Parker Institute was supported by a core grant from the Oak Foundation. Several authors reported receiving honoraria, grants, and other funding from Abbott, AbbVie, bioM\u00e9rieux, Brahms GmbH, and various sources. Full disclosures are noted in the original article.<\/p>\n
This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.<\/em><\/p>\n<\/div>\n<\/div>\n
\n
<<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"
TOPLINE: In a pooled analysis of 25 studies from 23 countries, a two-question screening tool demonstrated excellent diagnostic accuracy for identifying individuals with hidradenitis suppurativa (HS), with a pooled sensitivity of 0.88 and specificity of 0.86. METHODOLOGY: Researchers evaluated the diagnostic accuracy of a screening questionnaire validated and used in the Global HS Atlas (GHiSA) […]<\/p>\n","protected":false},"author":1,"featured_media":4679,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_daextam_enable_autolinks":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[2],"tags":[],"class_list":["post-4678","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/diyhaven858.wasmer.app\/wp-content\/uploads\/2026\/01\/gty-260116-screening-800x450.jpg","jetpack_sharing_enabled":true,"jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/posts\/4678","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/comments?post=4678"}],"version-history":[{"count":0,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/posts\/4678\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/media\/4679"}],"wp:attachment":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/media?parent=4678"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/categories?post=4678"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/tags?post=4678"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
TAKEAWAY:<\/h2>\n\n- Sensitivity (0.43-1.00) and specificity (0.15-1.00) values varied globally. The pooled sensitivity of the screening questionnaire was 0.88, indicating a high ability to detect HS. The pooled specificity was 0.86, showing good discrimination of individuals without HS.<\/li>\n
- The area under the summary receiver operating curve was 0.93, indicating excellent diagnostic accuracy.<\/li>\n
- The positive predictive value ranged from 0.05 to 1.00, and the negative predictive value ranged from 0.97 to 1.00, with 17 of 23 countries reporting a negative predictive value of 1.00.<\/li>\n
- The Quality Assessment of Diagnostic Accuracy Studies-2 tool assessment rated risk for bias as high for the \u201creference standard\u201d and for the \u201cpatient flow\u201d domain; there were applicability concerns for patient selection.<\/li>\n<\/ul>\n
IN PRACTICE:<\/h2>\n
\u201cThe results demonstrate a high diagnostic accuracy (pooled sensitivity, 0.88; and specificity, 0.86) of the screening questionnaire in detecting HS in healthy adults,\u201d the study authors wrote. This questionnaire, they concluded, \u201cmay prove useful in triaging, ensuring that only individuals fitting the criteria see specialized dermatological care.\u201d<\/p>\n
SOURCE:<\/h2>\n
The study was led by Dorra Bouazzi, Department of Dermatology, Zealand University Hospital, Roskilde, Denmark, and was published online on January 9 in the British Journal of Dermatology<\/em>.<\/p>\nLIMITATIONS:<\/h2>\n
The exclusive inclusion of GHiSA studies may have limited the generalizability of the findings. The study had a high risk for bias in reference standard and patient flow domains, which lowered the validity of the study. Additionally, the absence of likelihood ratios limited comprehensive assessment of the diagnostic test.<\/p>\n
DISCLOSURES:<\/h2>\n
Bouazzi reported receiving research grant support from Region Sjaelland \u2013 Medicinsporet. The Section for Biostatistics and Evidence-Based Research at the Parker Institute was supported by a core grant from the Oak Foundation. Several authors reported receiving honoraria, grants, and other funding from Abbott, AbbVie, bioM\u00e9rieux, Brahms GmbH, and various sources. Full disclosures are noted in the original article.<\/p>\n
This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.<\/em><\/p>\n<\/div>\n<\/div>\n
\n
<<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"
TOPLINE: In a pooled analysis of 25 studies from 23 countries, a two-question screening tool demonstrated excellent diagnostic accuracy for identifying individuals with hidradenitis suppurativa (HS), with a pooled sensitivity of 0.88 and specificity of 0.86. METHODOLOGY: Researchers evaluated the diagnostic accuracy of a screening questionnaire validated and used in the Global HS Atlas (GHiSA) […]<\/p>\n","protected":false},"author":1,"featured_media":4679,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_daextam_enable_autolinks":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[2],"tags":[],"class_list":["post-4678","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/diyhaven858.wasmer.app\/wp-content\/uploads\/2026\/01\/gty-260116-screening-800x450.jpg","jetpack_sharing_enabled":true,"jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/posts\/4678","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/comments?post=4678"}],"version-history":[{"count":0,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/posts\/4678\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/media\/4679"}],"wp:attachment":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/media?parent=4678"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/categories?post=4678"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/tags?post=4678"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
IN PRACTICE:<\/h2>\n
\u201cThe results demonstrate a high diagnostic accuracy (pooled sensitivity, 0.88; and specificity, 0.86) of the screening questionnaire in detecting HS in healthy adults,\u201d the study authors wrote. This questionnaire, they concluded, \u201cmay prove useful in triaging, ensuring that only individuals fitting the criteria see specialized dermatological care.\u201d<\/p>\n
SOURCE:<\/h2>\n
The study was led by Dorra Bouazzi, Department of Dermatology, Zealand University Hospital, Roskilde, Denmark, and was published online on January 9 in the British Journal of Dermatology<\/em>.<\/p>\n The exclusive inclusion of GHiSA studies may have limited the generalizability of the findings. The study had a high risk for bias in reference standard and patient flow domains, which lowered the validity of the study. Additionally, the absence of likelihood ratios limited comprehensive assessment of the diagnostic test.<\/p>\n Bouazzi reported receiving research grant support from Region Sjaelland \u2013 Medicinsporet. The Section for Biostatistics and Evidence-Based Research at the Parker Institute was supported by a core grant from the Oak Foundation. Several authors reported receiving honoraria, grants, and other funding from Abbott, AbbVie, bioM\u00e9rieux, Brahms GmbH, and various sources. Full disclosures are noted in the original article.<\/p>\n This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.<\/em><\/p>\n<\/div>\n<\/div>\n TOPLINE: In a pooled analysis of 25 studies from 23 countries, a two-question screening tool demonstrated excellent diagnostic accuracy for identifying individuals with hidradenitis suppurativa (HS), with a pooled sensitivity of 0.88 and specificity of 0.86. METHODOLOGY: Researchers evaluated the diagnostic accuracy of a screening questionnaire validated and used in the Global HS Atlas (GHiSA) […]<\/p>\n","protected":false},"author":1,"featured_media":4679,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_daextam_enable_autolinks":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[2],"tags":[],"class_list":["post-4678","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/diyhaven858.wasmer.app\/wp-content\/uploads\/2026\/01\/gty-260116-screening-800x450.jpg","jetpack_sharing_enabled":true,"jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/posts\/4678","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/comments?post=4678"}],"version-history":[{"count":0,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/posts\/4678\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/media\/4679"}],"wp:attachment":[{"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/media?parent=4678"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/categories?post=4678"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/diyhaven858.wasmer.app\/index.php\/wp-json\/wp\/v2\/tags?post=4678"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}LIMITATIONS:<\/h2>\n
DISCLOSURES:<\/h2>\n
\n
<<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"