{"id":87785,"date":"2026-05-01T01:02:34","date_gmt":"2026-05-01T01:02:34","guid":{"rendered":"https:\/\/diyhaven858.wasmer.app\/index.php\/combined-istent-infinite-phaco-lowers-iop-at-2-years\/"},"modified":"2026-05-01T01:02:34","modified_gmt":"2026-05-01T01:02:34","slug":"combined-istent-infinite-phaco-lowers-iop-at-2-years","status":"publish","type":"post","link":"https:\/\/diyhaven858.wasmer.app\/index.php\/combined-istent-infinite-phaco-lowers-iop-at-2-years\/","title":{"rendered":"Combined iStent infinite, phaco lowers IOP at 2 years"},"content":{"rendered":"<p> <br \/>\n<\/p>\n<div data-component=\"ArticleContent\">\n<div class=\"article__below-title\">\n<div class=\" article__posted-date\">\n<p>April 30, 2026<\/p>\n<p>2 min watch<\/p>\n<\/p><\/div>\n<div class=\"mobile-trust-box\">\n<div class=\"row\">\n<div class=\"col-12 col-md-5 d-xl-none\">\n<div class=\"trust-box\">\n<div class=\"trust-box-logo d-none d-md-block\">\n            <img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.healio.com\/~\/media\/h5\/feature\/news\/publogos\/osn.svg?la=en&amp;h=32&amp;w=145&amp;hash=C099A5ADC410818ECDF2097A4CD3C51F\" class=\"logo-img\" height=\"32\" alt=\"occular surgery news logo\" width=\"145\"\/>\n          <\/div>\n<\/p><\/div>\n<\/p><\/div>\n<div class=\"col-12 col-md-6 offset-md-1 offset-xl-0 col-xl-12\">\n<div class=\"email-alert-button-wrapper d-none\" data-component=\"EmailTopicAlert\" data-module=\"Subspecialty Email Topic Alerts Top\" data-manage-email-link=\"\/footer\/account-information\/my-account\/email-subscriptions-and-alerts#emailAlerts\">\n  <hidden data-setting-item=\"d265901d-6d37-49c7-a8f6-c7bf19a02509\"\/><br \/>\n  <hidden data-crm-source=\"Subspecialty Topic Alert\"\/><\/p>\n<div class=\"email-alert-button d-none\" data-topic-button=\"not-subscribed\">\n<p>&#13;<br \/>\n      <span data-module-track-action=\"Email Alerts TOP_Click_Healio News Article\" data-module-track-label=\"Email Alerts TOP_Healio News Article\">&#13;<br \/>\n        <i class=\"fas fa-plus-circle\"\/>&#13;<br \/>\n        Add topic to email alerts&#13;<br \/>\n      <\/span>&#13;\n    <\/p>\n<div class=\"email-alert-inner collapse ucf5adab57cc943069f1aea11ee3527ae\">\n<div class=\"email-alert-dialogue\">\n<p>&#13;<br \/>\n          Receive an email when new articles are posted on <span data-content=\"topic-title\"\/>&#13;\n        <\/p>\n<div class=\"d-none\" data-sign-up-type=\"unknown\">\n          Please provide your email address to receive an email when new articles are posted on <span data-content=\"topic-title\"\/>.<\/p><\/div>\n<\/p><\/div>\n<p>      <button type=\"button\" class=\"btn btn-primary\" data-loading-text=\"Loading &lt;i class=\" fa=\"\" fa-spinner=\"\" fa-spin=\"\">&#8220;&#13;<br \/>\n              data-action=&#8221;subscribe&#8221;&gt;&#13;<br \/>\n        Subscribe&#13;<br \/>\n      <\/button>\n    <\/div>\n<\/p><\/div>\n<div class=\"d-none\" data-topic-modal=\"failed\">    <strong>We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com.<\/strong>  <\/p>\n<p><button data-dismiss=\"modal\" class=\"btn btn-primary btn-lg btn-block\">Back to Healio<\/button><\/p>\n<\/div>\n<\/div><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/div>\n<h2>Key takeaways:<\/h2>\n<ul>\n<li>Mean IOP decreased from 16 mm Hg at baseline to approximately 14 mm Hg.<\/li>\n<li>Medication burden decreased from 1.25 to 0.75.<\/li>\n<\/ul>\n<p>WASHINGTON \u2014 At 2 years, trabecular micro-bypass implantation in combination with phacoemulsification yielded IOP reductions in patients with open-angle glaucoma, according to a presenter.<\/p>\n<p>At the American Society of Cataract and Refractive Surgery meeting,<b> <\/b><b>Zachary D. Vest, MD,<\/b> of Mile High Eye Institute, told Healio that the iStent infinite (Glaukos) with phacoemulsification was evaluated in an unmasked, nonrandomized, retrospective, consecutive study in a consistent cohort of 27 eyes that had 24-month data.<\/p>\n<p>According to Vest, mean IOP decreased from 16 mm Hg at baseline to approximately 14 mm Hg. There was also a reduction in medication burden.<\/p>\n<p>\u201cThe medication burden decreased from 1.25 medications down to 0.75 medications on average,\u201d he told Healio. \u201cApproximately 93% of patients had a pressure less than 18 mm Hg at the completion of the 2 years.\u201d <\/p>\n<p>The complication rate was low, with no reported intraocular complications or secondary interventions related to adverse events, Vest said.<\/p>\n<p>\u201cOverall, this study showed good IOP reduction even in a study population starting out with a lower intraocular pressure than a normal MIGS study. There was a good decrease in overall medication requirements and a low risk of secondary intervention at 2 years,\u201d Vest told Healio.<\/p>\n<div class=\"article__content--footer\">\n<div class=\"publisher-logo\">\n    <span>Published by:<\/span><br \/>\n    <img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.healio.com\/~\/media\/h5\/feature\/news\/publogos\/osn.svg?la=en&amp;h=32&amp;w=145&amp;hash=C099A5ADC410818ECDF2097A4CD3C51F\" class=\"logo-img\" height=\"32\" alt=\"occular surgery news logo\" width=\"145\"\/>\n  <\/div>\n<div class=\"sources-references-disclosures\">\n<h3>Sources\/Disclosures<\/h3>\n<h2> Source: <\/h2>\n<p class=\"citation\">Vest ZD, et al. Two year outcomes after third-generation trabecular micro-bypass performed with phacoemulsification in patients with open-angle glaucoma. Presented at: American Society of Cataract and Refractive Surgery meeting; April 10-13, 2026; Washington.<\/p>\n<div class=\"disclosures\">\n<p>&#13;<br \/>\n        <strong> Disclosures: <\/strong>&#13;<br \/>\n        Vest reports consulting for and receiving research funding from Alcon and Glaukos. &#13;\n      <\/p>\n<\/p><\/div>\n<\/div>\n<p><!-- Healio AI Widget --><\/p>\n<div class=\"healio-ai-component-inline\" data-no-ads=\"true\" data-module-track-category=\"Healio AI\" data-module-track-action=\"Click\" data-module-track-label=\"Access Healio Ai from component - News_AI Component - In-Content (all devices)\">\n<div class=\"healio-ai-content\">\n    <img decoding=\"async\" src=\"https:\/\/m3.healio.com\/~\/media\/images\/healio-ai\/healio-ai_logo.svg\" alt=\"Healio AI\" class=\"healio-ai-logo\"\/><\/p>\n<p><strong>Ask a clinical question<\/strong> and tap into <strong>Healio AI&#8217;s knowledge<\/strong> base.<\/p>\n<ul>&#13;<\/p>\n<li>PubMed, enrolling\/recruiting trials, guidelines<\/li>\n<p>&#13;<\/p>\n<li>Clinical Guidance, Healio CME, FDA news<\/li>\n<p>&#13;<\/p>\n<li>Healio&#8217;s exclusive daily news coverage of clinical data<\/li>\n<p>&#13;\n    <\/ul>\n<p>    <button class=\"healio-ai-button\" onclick=\"window.location.href=\" https:=\"\">Learn more<\/button>\n  <\/div>\n<\/div>\n<div class=\"email-alert-button-wrapper d-none\" data-component=\"EmailTopicAlert\" data-module=\"Subspecialty Email Topic Alerts Top\" data-manage-email-link=\"\/footer\/account-information\/my-account\/email-subscriptions-and-alerts#emailAlerts\">\n  <hidden data-setting-item=\"d265901d-6d37-49c7-a8f6-c7bf19a02509\"\/><br \/>\n  <hidden data-crm-source=\"Subspecialty Topic Alert\"\/><\/p>\n<div class=\"email-alert-button d-none\" data-topic-button=\"not-subscribed\">\n<p>&#13;<br \/>\n      <span data-module-track-action=\"Email Alerts TOP_Click_Healio News Article\" data-module-track-label=\"Email Alerts TOP_Healio News Article\">&#13;<br \/>\n        <i class=\"fas fa-plus-circle\"\/>&#13;<br \/>\n        Add topic to email alerts&#13;<br \/>\n      <\/span>&#13;\n    <\/p>\n<div class=\"email-alert-inner collapse ucf5adab57cc943069f1aea11ee3527ae\">\n<div class=\"email-alert-dialogue\">\n<p>&#13;<br \/>\n          Receive an email when new articles are posted on <span data-content=\"topic-title\"\/>&#13;\n        <\/p>\n<div class=\"d-none\" data-sign-up-type=\"unknown\">\n          Please provide your email address to receive an email when new articles are posted on <span data-content=\"topic-title\"\/>.<\/p><\/div>\n<\/p><\/div>\n<p>      <button type=\"button\" class=\"btn btn-primary\" data-loading-text=\"Loading &lt;i class=\" fa=\"\" fa-spinner=\"\" fa-spin=\"\">&#8220;&#13;<br \/>\n              data-action=&#8221;subscribe&#8221;&gt;&#13;<br \/>\n        Subscribe&#13;<br \/>\n      <\/button>\n    <\/div>\n<\/p><\/div>\n<div class=\"d-none\" data-topic-modal=\"failed\">    <strong>We were unable to process your request. 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